A student researched lab analysis about the synthesis and characterization of aspirin by measuring the melting point as well as taking a uv spectroscopy. Carbon introduction aspirin is a pain relieving compound that most students will be familiar with, thus its synthesis gives students an insight into how chemistry. Purpose: to synthesize aspirin, a common analgesic drug, via nucleophilic acid-catalyzed substitution reaction of salicyclic acid with acetic anhydride. The synthesis of aspirin chemistry standard level lab report data collection and processing and conclusion and evaluation date: december 8th, 2011. An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples. Synthesis and analysis of aspirin 3 add 50 ml of acetic anhydride and 5 drops of 85% phosphoric acid swirl the mixture if necessary, use a sparingly small amount. Synthesis the synthesis of aspirin is classified as an esterification reaction salicylic acid is treated with acetic anhydride, an acid derivative.
Aspirin or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and. Aspirin synthesis lab by abigail arrigo, alexis arrigo, christian bruns, alissa lockwood, and justin rose objective 1 the first objective of this lab was to. The key compound in the synthesis of aspirin, salicylic acid, is prepared from phenol by a process discovered over 100 years ago by the german chemist hermann kolbe. Aspirin is the prototypical analgesic used in the treatment of mild to moderate pain it has anti-inflammatory and antipyretic properties and acts as an inhibitor of.
Decompose residual acetic anhydride if an oil appears instead of a solid, reheat the flask in the hot water bath until the oil disappears and again cool. Mechanism-green synthesis using microwave in a clean dry 50 ml round bottomed flask, take 05g of salicylic acid add to this 2ml of acetic anhydride, swirl and add. Synthesis of aspirin in this experiment, aspirin will be made by the esterification of salicylic acid the product will be isolated and a thin layer chromatography. Synthesis of aspirin the chemical company for which you work has developed a new laboratory method for synthesising aspirin which produces a high yield of pure.
Here are some additional questions relating to aspirin synthesis: helmenstine, anne marie, phd how to make aspirin - acetylsalicylic acid thoughtco. The goal of this experiment was to synthesize aspirin in this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic. Chem-a #22: in this experiment, you will synthesize a sample of acetylsalicylic acid (aspirin) calculate the percent yield of your synthesis measure the melting. A study guide for the synthesis of aspirin ideal for students taking chem 40 or organic chemistry who are doing their pre-laboratory and post-laboratory reports with.
Aspirin synthesis in laboratory - duration: 7:57 bio-trax 3,565 views 7:57 acetylsalicylic acid (asa) extraction from aspirin tablets - duration: 4:44.
Procedure synthesis of aspirin heat a large beaker full of water on the hot plate to 75-85 ˚ c leave the hot plate on and the beaker on the hot plate for step 5. In this experiment, you will prepare aspirin from salicylic acid and acetic anhydride using sulfuric acid as a catalyst you will determine the percent yield of. Part of ncssm core collection: this video shows the synthesis of aspirin please attribute this work as being created by the north. Aspirin (2nd edition) compiled by david lewis edited by colin osborne and maria pack designed by imogen bertin and sara roberts first published by the royal society. A student researched lab experiment about the synthesis of aspirin. 1 aspirin is the common name for the compound acetylsalicylic acid, widely used as a fever reducer and as a pain killer salicylic acid, whose name comes from salix. Synthesis of aspirin synthesis purification characterization aspirin: some background patented by bayer in 1893 one of the oldest drugs one of the most consumed drugs.
Chem 322: synthesis of aspirin introduction: aspirin is one of the milder and least expensive pain relievers available today, americans spend. I introduction organic synthesis is the process where a desired organic compound is constructed or prepared from commercially available materials. An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples it is the two-step. Los angeles city college chemistry 51 fall 2005 3093 1 experiment 11 synthesis and analysis of aspirin introduction aspirin is most widely sold over-the-counter drug.